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Match preview
After running riot in Serie A on Sunday, will Atalanta avoid falling at the first hurdle in the Coppa Italia?
At the weekend, la Dea demolished Salernitana 8-2, becoming the first club to score 8+ in a Serie A match for 27 years.
Jérémie Boga, Ademola Lookman, Giorgio Scalvini, Teun Koopmeiners, Rasmus Højlund, Éderson and Nadir Zortea all on target on, what was, an historic evening in Bergamo.
That made it back-to-back wins for Gian Piero Gasperini’s side, who’d only won one of their previous six beforehand.
This lifts I Nerazzurri up to sixth, ahead of a huge clash with Juventus in Turin this forthcoming Sunday night.
In this competition, Atalanta are chasing their first piece of major silverware since 1963.
Spezia meanwhile are competing in the round of 16 for only the fifth time in 81 years, overcoming Como and Brescia to get here.
I Bianchi are currently 15th in Serie A, following a crucial 1-0 victory over Torino on Sunday; M’Bala Nzola’s penalty the difference.
Just 15 days ago, these two played out a 2-2 draw at Stadio Alberto Picco, with Mario Pašalić snatching a 92nd minute equaliser.
This time at Stadio Atleti Azzurri d’Italia, Atalanta will be seeking to make home advantage count.
The prize on offer for the winners is a trip to San Siro to take on holders Inter in the quarter-finals.