Liverpool head into the game on a fine run of form that has seen them win their last five outings.
This run has moved Liverpool up to 5th in the Premier League and to within four points of Manchester United and the Champions League places.
However, Manchester United still have a game in hand on the Reds, meaning that gap could go to seven points with just four games to play.
As a result, Liverpool have to win their remaining four games to stand any chance of securing a top-four berth.
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Predicted Liverpool line-up vs Brentford
Liverpool team news vs Brentford
Thiago is out for the remainder of the season after undergoing surgery.
Stefan Bajcetic and Calvin Ramsay are also set to miss the rest of 2022/23 with groin and knee issues respectively.
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