Lazio suffered their worst ever home defeat as champions Inter Milan stormed to a 6-0 win in Rome.
Lazio started the night level on points with Inter and are top of the Europa League table but had no answer to a stunning attacking display from Simone Inzaghi’s side.
They were unbeaten in 12 home games and had not lost in front of their own fans since March.
Hakan Calhanoglu put Inter in front from the spot in the 41st minute, after a penalty award for handball, and Federico Dimarco doubled the lead before the break with a volley.
Nicolo Barella slotted home to make it 3-0 six minutes after the restart before Denzel Dumfries netted two minutes later and Carlos Augusto and Marcus Thuram completed the rout late on.
Inter remain third in the standings with 34 points from 15 matches and trail leaders Atalanta by three points with a game in hand.
Lazio’s previous record home defeat was a 5-0 loss to Fiorentina in 1959.
Their three biggest Serie A defeats are all against Internazionale: this defeat going after 8-1 (in 1934) and 7-0 (in 1961) defeats in Milan.