Arsenal will host holders Manchester United in the third round of the FA Cup.
The Premier League giants, who have 27 FA Cup triumphs between them, will go head-to-head at the Emirates after being pitted against each other in Monday’s draw.
Arsenal’s rivals Tottenham face a much different task as they travel to National League Tamworth, who are the lowest-ranked team remaining.
The Staffordshire-based outfit beat League One side Burton on penalties in the second round after a 1-1 draw, having stunned Championship Huddersfield in round one.
Manchester City host Class of 92-owned Salford City at the Etihad, while Premier League leaders Liverpool are also at home to Accrington.
Chelsea are another big side to have beeb handed a favourable tie as they welcome League Two Morecambe to Stamford Bridge.
Dagenham and Redbridge, the only other remaining non-league side, go to Championship Millwall with League Two strugglers paired against Premier League Newcastle at St James’ Park.
FA Cup third-round draw in full
Southampton v Swansea City
Arsenal v Manchester United
Exeter City v Oxford United
Leyton Orient v Derby County
Reading v Burnley
Aston Villa v West Ham
Norwich City v Brighton & Hove Albion
Manchester City v Salford
Millwall v Dagenham & Redbrige
Liverpool v Accrington Stanley
Bristol City v Wolverhampton Wanderers
Preston North End v Charlton Athletic
Chelsea v Morecambe
Middlesbrough v Blackburn Rovers
Bournemouth v West Bromwich Albion
Mansfield Town v Wigan Athletic
Tamworth v Tottenham
Hull City v Doncaster Rovers
Sunderland v Stoke City
Leicester City v Queens Park Rangers
Brentford v Plymouth Argyle
Coventry City v Sheffield Wednesday
Newcastle United v Bromley
Everton v Peterborough United
Wycombe Wanderers v Portsmouth
Birmingham City v Lincoln City
Leeds United v Harrogate Town
Nottingham Forest v Luton Town
Sheffield United v Cardiff City
Ipswich Town v Bristol Rovers
Fulham v Watford
Crystal Palace v Stockport County