West Ham head into the game having lost their last two Premier League games.
This means the Hammers still have the threat of relegation hanging over them.
West Ham are 15th in the division with 34 points heading into the match. 18th place Leicester City, meanwhile, are just five points behind them with five games left to play.
As a result, a loss to Manchester City could see that gap close to just two points with four games to go, which is a position David Moyes’ side do not want to be in.
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Predicted West Hamline-up vs Manchester City
West Ham team news vs Manchester City
West Ham are set to be without two players when they take on Manchester City.
Gianluca Scamacca had a knee injury which has likely ruled him out for the remainder of the campaign.
Arsenal face competition from Bayern Munich for Premier League star